Research Team: A/Prof Tina Skinner , Dr Marloes Nitert Dekker, Prof David Jenkins, Prof Jeff Coombes and Mr Alexander Boytar
Years: 2021-2022
The human gut microbiome influences tumour growth and spread in individuals with colorectal cancer, as well as indirectly influencing the risks of secondary cancers via inflammation and immune function. Exercise can mediate the burden of colorectal cancer, risk of recurrence and cancer-related mortality.
Exercise interventions have been shown to improve microbiome functional diversity, yet no studies exist in cancer populations. This study will examine changes in the microbiome, and its relationship with changes in body composition and inflammation, in response to high-intensity interval training in colorectal cancer survivors.
Funding Body: The University of Newcastle CRE